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Pippali (Piper longum)

Anti-arthritic: Piperine reduces inflammation and joint damage by inhibiting the expression of interleukin (IL6), matrix metalloproteinase (MMP13) and the production of prostaglandin PGE2.

Anti-osteoporotic: Piperine increases the amount of collagenous fibers in the matrix of bone tissue and areas of regeneration for stronger bones.

Enhance Digestion: Piperine remarkably increases pancreatic lipase activity and stimulates pancreatic amylase, trypsin, and chymotrypsin for healthy digestion.

Anti-asthmatic: Piperine reduces airway inflammation and hyper-responsiveness by inhibiting the release of Th2- mediated cytokines (IL‐4, IL‐5, IL‐13) and eosinophil infiltration.

Anti-histaminic: Acts as antihistaminic by inhibiting antigen induced histamine release and inhibits antigen induced degranulation.

Hepatoprotective: Piperine protects liver by virtue of its antioxidant properties, it reduces lipid peroxidation and preserve the depletion of glutathione in the liver.

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