Pippali (Piper longum)
Anti-arthritic: Piperine reduces inflammation and joint damage by inhibiting the expression of interleukin (IL6), matrix metalloproteinase (MMP13) and the production of prostaglandin PGE2.
Anti-osteoporotic: Piperine increases the amount of collagenous fibers in the matrix of bone tissue and areas of regeneration for stronger bones.
Enhance Digestion: Piperine remarkably increases pancreatic lipase activity and stimulates pancreatic amylase, trypsin, and chymotrypsin for healthy digestion.
Anti-asthmatic: Piperine reduces airway inflammation and hyper-responsiveness by inhibiting the release of Th2- mediated cytokines (IL‐4, IL‐5, IL‐13) and eosinophil infiltration.
Anti-histaminic: Acts as antihistaminic by inhibiting antigen induced histamine release and inhibits antigen induced degranulation.
Hepatoprotective: Piperine protects liver by virtue of its antioxidant properties, it reduces lipid peroxidation and preserve the depletion of glutathione in the liver.