Anti-inflammatory and Analgesic: Negundo leaves have anti-inflammatory and analgesic activity mediated via PG synthesis inhibition, antihistamine, membrane stabilizing and antioxidant activity.

Anti-tussive: In non-productive cough nirgundi significantly inhibits cough reflexes with its peripheral anti-tussive action and provides instant relief from dry cough.

Anti-osteoporotic: Vitexdoin in nirgundi modulate the bone formation and resorption process through increasing osteoblast proliferation and production of alkaline phosphatase.